Endocrine Abstracts

Infection with HIV may be complicated by hypoinsulinaemic hypoglycaemia. We report, for the first time, a case of hyperinsulinaemic hypoglycaemia in a pregnant woman with HIV. A 30 year old patient was diagnosed to have AIDS during the 8th week of her fourth pregnancy and was commenced on standard antiretroviral therapy. At 27 weeks of pregnancy she presented with a grand mal seizure and was found to be hypoglycaemic with venous blood glucose of 1.2mmol/L with inappropriately ...

Infection with HIV may be complicated by hypoinsulinaemic hypoglycaemia. We report, for the first time, a case of hyperinsulinaemic hypoglycaemia in a pregnant woman with HIV. A 30 year old patient was diagnosed to have AIDS during the 8th week of her fourth pregnancy and was commenced on standard antiretroviral therapy. At 27 weeks of pregnancy she presented with a grand mal seizure and was found to be hypoglycaemic with venous blood glucose of 1.2mmol/L with inappropriately ...

Introduction: Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant multi-glandular tumour syndrome, caused by RET germline mutations.We present a family with three affected generations identified by predictive testing.Index case and cohort details: A 40-year-old lady referred to ENT clinic with a swelling in the neck. Ultrasound confirmed multinodular goitre with FNAC-THY3. Diagnostic hemithyroidectomy was followed by total thyroidectomy f...

We report a falsely elevated blood spot thyrotrophin (TSH) concentration caused by a TSH-IgG complex. A routine blood spot screen returned a whole blood TSH of 213 mU/l from a one week-old neonate using the Wallac DELFIA method. Measurement in serum confirmed elevated TSH (826 mU/l, Roche Elecsys assay) but free thyroxine (17.2 pmol/l) was normal. The baby’s mother was clinically euthyroid but also showed discordant high serum TSH (287 mU/l) with normal free thyroxine (13...